List of Endocrine Glands and their Hormones

 

Gland

Secretion

Function

Hyposecretion

Hypersecretion

Adrenal cortex

 

Aldosterone

Regulates salt, water balance, and blood pressure

addison's disease can occur

hypertension & edema, low levels of K, alkalosis

Cortisol

Controls key functions in the body; acts as an anti-inflammatory; maintains blood sugar levels, blood pressure, and muscle strength; regulates salt and water balance

addison's disease: fatigue, nausea, skin darkening, low BP, h2o-electrolyte imbalance, low blood sugar, dizziness, muscle weakness

and hypoglycemia

cushing's syndrome: weight gain, "buffalo hump", purple stretch marks, rounded face, excessive sweating/hunger, acne, insomnia, depression

and hyperglycemia

Adrenal medulla

Norepinephrine and epinephrine

Has the same effects on target organs as stimulation by the sympathetic nerves but is longer lasting

 

 

Hypothalamus

Growth hormone releasing hormone (GHRH)

Regulates growth hormone release in the pituitary gland

 

 

Thyrotropin releasing hormone (TRH)

Regulates thyroid stimulating hormone release in the pituitary gland

 

 

Gonadotropin releasing hormone (GnRH)

Regulates LH/FSH production in the pituitary gland

 

 

Corticotropin releasing hormone (CRH)

Regulates adrenocorticotropin release in the pituitary gland

 

 

Growth hormone inhibitory hormone (GHIH)

Inhibits  growth hormone secretion.

 

 

Dopamine or prolactin-inhibiting factor (PIF)

Inhibits prolactin secretion.

 

 

Kidneys

Renin and angiotensin

Controls blood pressure, both directly and also by regulating aldosterone production from the adrenal glands

low sodium levels, potassium retention

hypertension, sodium retention, kidney dysfunction

Erythropoietin

Affects red blood cell (RBC) production

 

 

Ovaries

Estrogen

Affects development of female sexual characteristics and reproductive development, important for functioning of uterus and breasts; also protects bone health

infertility

multiple births

Progesterone

Stimulates the lining of the uterus for fertilization; prepares the breasts for milk production

infertility

possible endometriosis

Pancreas

 

Glucagon

Raises blood sugar levels

possible hypoglycemia

possible hyperglycemia

Insulin

Lowers blood sugar levels; stimulates metabolism of glucose, protein, and fat

diabetes mellitus: too much glucose in blood, headaches, blurry vision, trouble concentrating, frequent urination, thirst, hunger, glucose in urine, weight loss

hypoglycemia: not enough glucose in blood, fatigue, shakiness, light-headed, hungry, confused, lip tingling, dry mouth

Somatostatin

Regulates various physiological functions and exerts inhibitory action on numerous secondary hormones such as glucagon and insulin. It also regulates gastrointestinal tract activities like gastrointetinal motility and secretion of gastrin and secretin

 

 

Parathyroid glands

Parathyroid hormone (PTH)

Most important regulator of blood calcium levels

 

 

Pineal gland

Melatonin

Releases melatonin during night hours to help with sleep

possible difficulty sleeping

possible sleepiness

Pituitary gland

 

Antidiuretic hormone (ADH) or vasopressin

Affects water retention in kidneys; controls blood pressure

concentrated urine, possible kidney stones

diabetes insipidus: excessive urination, thirst

Adrenocorticotropic hormone (ACTH)

Controls production of sex hormones (estrogen in women and testosterone in men) and the production of eggs in women and sperm in men.

Addison’s disease

Cushing’s syndrome; tumours in the adrenal cortex

Growth hormone (GH)

Affects growth and development; stimulates protein production; affects fat distribution

pituitary dwarfism

gigantism; acromegaly

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH)

Controls production of sex hormones (estrogen in women and testosterone in men) and the production of eggs in women and sperm in men

infertility, amenorrhea, impotence, low sperm count

multiple births, early sexual maturation, acne

Oxytocin

Stimulates contraction of uterus and milk ducts in the breast

possible link to autism / depression

can hasten labor, risk of prostatic tumors

Prolactin

Initiates and maintains milk production in breasts; impacts sex hormone levels

inability to nurse baby, erectile dysfunction, low sperm count, anxiety, premature ejaculation

infertility, decreased libido, excess milk, amenorrhea

Thyroid-stimulating hormone (TSH)

Stimulates the production and secretion of thyroid hormones

weight gain, slowed heart rate, slowed metabolism, feeling sluggish/cold

weight loss, palpitations, anxiety, heat intolerance

Testes

Testosterone

Develop and maintain male sexual characteristics and maturation

sterility

over masculinization: hairy, increased muscle mass, aggressive behavior

Thymus

Humoral factors

Helps develop the lymphoid system

 

 

Thyroid gland

Thyroxine (T4)  and Triiodothyronine (T3)

Controls metabolism; also affects growth, maturation, nervous system activity, and metabolism

in kids = cretinism: like dwarfism, but proportions are childlike & mental retardation

in adults = myxedema: physical & mental sluggishness, poor muscle tone, puffy face, obesity, cold

and goiter: enlargement of thyroid gland

 

Calcitonin

Promotes calcium deposition in the bones;  reduces the calcium levels present in the blood and tissue fluid