Gland |
Secretion |
Function |
Hyposecretion |
Hypersecretion |
Adrenal cortex
|
Aldosterone |
Regulates salt, water balance, and blood pressure |
addison's disease can occur |
hypertension & edema, low levels of K, alkalosis |
Cortisol |
Controls key functions in the body; acts as an anti-inflammatory; maintains blood sugar levels, blood pressure, and muscle strength; regulates salt and water balance |
addison's disease: fatigue, nausea, skin darkening, low BP, h2o-electrolyte imbalance, low blood sugar, dizziness, muscle weakness and hypoglycemia |
cushing's syndrome: weight gain, "buffalo hump", purple stretch marks, rounded face, excessive sweating/hunger, acne, insomnia, depression and hyperglycemia |
|
Adrenal medulla |
Norepinephrine and epinephrine |
Has the same effects on target organs as stimulation by the sympathetic nerves but is longer lasting |
|
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Hypothalamus |
Growth hormone releasing hormone (GHRH) |
Regulates growth hormone release in the pituitary gland |
|
|
Thyrotropin releasing hormone (TRH) |
Regulates thyroid stimulating hormone release in the pituitary gland |
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|
|
Gonadotropin releasing hormone (GnRH) |
Regulates LH/FSH production in the pituitary gland |
|
|
|
Corticotropin releasing hormone (CRH) |
Regulates adrenocorticotropin release in the pituitary gland |
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|
|
Growth hormone inhibitory hormone (GHIH) |
Inhibits growth hormone secretion. |
|
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Dopamine or prolactin-inhibiting factor (PIF) |
Inhibits prolactin secretion. |
|
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|
Kidneys |
Renin and angiotensin |
Controls blood pressure, both directly and also by regulating aldosterone production from the adrenal glands |
low sodium levels, potassium retention |
hypertension, sodium retention, kidney dysfunction |
Erythropoietin |
Affects red blood cell (RBC) production |
|
|
|
Ovaries |
Estrogen |
Affects development of female sexual characteristics and reproductive development, important for functioning of uterus and breasts; also protects bone health |
infertility |
multiple births |
Progesterone |
Stimulates the lining of the uterus for fertilization; prepares the breasts for milk production |
infertility |
possible endometriosis |
|
Pancreas
|
Glucagon |
Raises blood sugar levels |
possible hypoglycemia |
possible hyperglycemia |
Insulin |
Lowers blood sugar levels; stimulates metabolism of glucose, protein, and fat |
diabetes mellitus: too much glucose in blood, headaches, blurry vision, trouble concentrating, frequent urination, thirst, hunger, glucose in urine, weight loss |
hypoglycemia: not enough glucose in blood, fatigue, shakiness, light-headed, hungry, confused, lip tingling, dry mouth |
|
Somatostatin |
Regulates various physiological functions and exerts inhibitory action on numerous secondary hormones such as glucagon and insulin. It also regulates gastrointestinal tract activities like gastrointetinal motility and secretion of gastrin and secretin |
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|
Parathyroid glands |
Parathyroid hormone (PTH) |
Most important regulator of blood calcium levels |
|
|
Pineal gland |
Melatonin |
Releases melatonin during night hours to help with sleep |
possible difficulty sleeping |
possible sleepiness |
Pituitary gland
|
Antidiuretic hormone (ADH) or vasopressin |
Affects water retention in kidneys; controls blood pressure |
concentrated urine, possible kidney stones |
diabetes insipidus: excessive urination, thirst |
Adrenocorticotropic hormone (ACTH) |
Controls production of sex hormones (estrogen in women and testosterone in men) and the production of eggs in women and sperm in men. |
Addison’s disease |
Cushing’s syndrome; tumours in the adrenal cortex |
|
Growth hormone (GH) |
Affects growth and development; stimulates protein production; affects fat distribution |
pituitary dwarfism |
gigantism; acromegaly |
|
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) |
Controls production of sex hormones (estrogen in women and testosterone in men) and the production of eggs in women and sperm in men |
infertility, amenorrhea, impotence, low sperm count |
multiple births, early sexual maturation, acne |
|
Oxytocin |
Stimulates contraction of uterus and milk ducts in the breast |
possible link to autism / depression |
can hasten labor, risk of prostatic tumors |
|
Prolactin |
Initiates and maintains milk production in breasts; impacts sex hormone levels |
inability to nurse baby, erectile dysfunction, low sperm count, anxiety, premature ejaculation |
infertility, decreased libido, excess milk, amenorrhea |
|
Thyroid-stimulating hormone (TSH) |
Stimulates the production and secretion of thyroid hormones |
weight gain, slowed heart rate, slowed metabolism, feeling sluggish/cold |
weight loss, palpitations, anxiety, heat intolerance |
|
Testes |
Testosterone |
Develop and maintain male sexual characteristics and maturation |
sterility |
over masculinization: hairy, increased muscle mass, aggressive behavior |
Thymus |
Humoral factors |
Helps develop the lymphoid system |
|
|
Thyroid gland |
Thyroxine (T4) and Triiodothyronine (T3) |
Controls metabolism; also affects growth, maturation, nervous system activity, and metabolism |
in kids = cretinism: like dwarfism, but proportions are childlike & mental retardation in adults = myxedema: physical & mental sluggishness, poor muscle tone, puffy face, obesity, cold and goiter: enlargement of thyroid gland |
|
Calcitonin |
Promotes calcium deposition in the bones; reduces the calcium levels present in the blood and tissue fluid |
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GK Questions for SBI PO, CAT, RRB, Clerk, NDA, RBI Assistant, SSC, CGL, PSC and other Competitive Examinations.